Jennifer Aniston, Reese Witherspoon "Terrified" of Chelsea Handler

Chelsea Handler is the alpha female of Hollywood!

"She's the queen bee right now," an insider says of the acerbic Chelsea Lately host, who, in the last few years, has befriended Jennifer Aniston and Reese Witherspoon (her co-star in This Means War).

PHOTOS: Celebs and their BFFs

Given Handler's reputation and sharp tongue, Aniston and Witherspoon are reportedly "terrified of her and kiss her ass because they want to stay on her good side!"

PHOTOS: Jen Aniston's other A-list BFF

Not to mention, the E! personality already has her eye on another A-lister to join their group!

Find out who it is in the clip above where Us' Ian Drew and special guest Coco Austin from Ice Loves Coco dish about the buzziest items in Hollywood right now!

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